PHBP6

Q-omics provides the consensus-scored PHBP6 profile across patient tissues and cancer cell-line models. PHBP6 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in LUAD. Additionally, PHBP6 RNA expression shows 2,440 significant pathway-activity associations, with the highest sampling consensus in ESCA. Together, these results highlight LUAD, and ESCA as cancer lineages where PHBP6 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes PHBP6 survival associations across molecular data types. PHBP6 RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

PHBP6 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	8	LUAD (123)	view →

This table ranks reproducible PHBP6 RNA expression–survival associations across cancer types. High PHBP6 expression shows unfavorable associations in LUAD, BLCA, PAAD, UCEC, LIHC and KIRC. The LUAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LUAD as the clearest survival context for PHBP6 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	0.254	0.713	<.001	123	view →
BLCA	DFS	Tertile	III,IV	0.137	0.574	.001	72	view →
PAAD	DFS	Tertile	All	0.068	0.484	<.001	72	view →
UCEC	OS	Tertile	II,III,IV	0.190	0.768	.001	72	view →
LIHC	OS	Tertile	All	0.028	0.775	<.001	45	view →
KIRC	DFS	Tertile	III,IV	0.224	0.654	.015	18	view →

Pink = unfavorable, green = favorable. all 8 lineages →

PHBP6-LUAD (OS)

Explore this curve interactively →