SNORD115-15

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD115-15 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-15-associated genes across cancer lineages are GEMIN2P2, LINC01967, and MTND2P8. Each is linked with SNORD115-15 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-15-to-partner and partner-to-SNORD115-15 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-15→partner) and Y-score (partner→SNORD115-15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMGEMIN2P2 →+0.052+3.408<.001.00931
SKCMLINC01967 →+0.731+3.709.004.00731
SKCMMTND2P8 →+0.052+3.717<.001.00531
SKCMCXXC4-AS1 →+0.058+4.022<.001.00331
UCECMIR4476 →+0.736+8.066<.001.00731
SKCMXAGE2 →+1.854+3.573<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

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