SNORD115-13

Across TCGA patient cohorts, SNORD115-13 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible SNORD115-13-associated genes across cancer lineages are RN7SKP221, RN7SKP293, and CES1P2. Each is linked with SNORD115-13 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-13-to-partner and partner-to-SNORD115-13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP221 grouped by SNORD115-13-low versus SNORD115-13-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-13→partner) and Y-score (partner→SNORD115-13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SKP221 →	+0.049	+4.186	<.001	.007	3	1
SKCM	RN7SKP293 →	+0.059	+4.411	<.001	.005	3	1
SKCM	CES1P2 →	+0.080	+2.701	.008	.007	3	1
SKCM	SNORA70D →	+0.131	+3.990	<.001	.009	3	1
SKCM	MIR6788 →	+0.281	+5.421	<.001	.001	3	1
LUSC	MIR374A →	+0.521	+6.438	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

RN7SKP221 by SNORD115-13 expression — SKCM

Explore this box plot interactively →