Q-omics provides the consensus-scored MIR374A profile across patient tissues and cancer cell-line models. MIR374A expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in THCA. Additionally, MIR374A RNA expression shows 7,198 significant gene co-expression associations, with the highest sampling consensus in BRCA. Together, these results highlight THCA, and BRCA as cancer lineages where MIR374A shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MIR374A survival associations across molecular data types. MIR374A RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MIR374A data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	9	THCA (45)	view →

This table ranks reproducible MIR374A RNA expression–survival associations across cancer types. High MIR374A expression shows unfavorable associations in THCA, COAD, UCEC, LUSC and KIRP, but favorable associations in STAD. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify THCA as the clearest survival context for MIR374A RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	All	0.156	0.820	.001	45	view →
COAD	OS	Tertile	IV	0.045	0.659	<.001	45	view →
UCEC	OS	Tertile	All	0.810	0.931	.008	42	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
KIRP	OS	Tertile	All	0.740	0.954	.002	24	view →
STAD	DFS	Quartile	IV	1.000	0.229	.002	20	view →

Pink = unfavorable, green = favorable. all 9 lineages →

MIR374A-THCA (DFS)

Kaplan–Meier survival curve for MIR374A RNA expression in THCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MIR374A in patient tissues and cancer cell lines. In patient samples, MIR374A shows the broadest associations at the RNA and protein expression levels, with BRCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	7,198	BRCA (3957)	view →
Function (RNA)	6,250	STAD (5741)	view →
▼Mutation
RNA	2	UCEC (2)	view →