SNORD115-11

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD115-11 mutation is significantly associated with the RNA expression of many other genes, with 75 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORD115-11-associated genes across cancer lineages are RNU6-342P, RNA5SP419, and RNU6-653P. Each is linked with SNORD115-11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-11-to-partner and partner-to-SNORD115-11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-11→partner) and Y-score (partner→SNORD115-11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-342P →+0.452+3.418<.001.00232
UCECRNA5SP419 →+1.124+3.077<.001.00532
SKCMRNU6-653P →+0.363+4.075<.001.00432
LUSCRNU6-1313P →+0.515+6.191<.001.00132
LUSCRNA5SP303 →+0.334+6.733<.001<.00132
UCECRNU4-5P →+0.389+2.850.003.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 75 associations by consensus.

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