Across TCGA pan-cancer cohorts, SNORD115-11 RNA is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SNORD115-11 data layer compared with 3 for mutation status.

The strongest signal is observed in kidney chromophobe (KICH), where higher SNORD115-11 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNORD115-11 expression acts as an unfavorable survival marker.

KICH and BRCA are the cancer types where SNORD115-11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.162	0.862	.014	30	view →
BRCA	DFS	Tertile	II,III,IV	0.321	0.889	<.001	30	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SNORD115-11 tumor-vs-normal RNA expression · all SNORD115-11 data types