Across TCGA patient cohorts, SNORD114-28 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SNORD114-28-associated genes across cancer lineages are DEFB107B, MBD3L4, and MIR495. Each is linked with SNORD114-28 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD114-28-to-partner and partner-to-SNORD114-28 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD114-28→partner) and Y-score (partner→SNORD114-28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DEFB107B →	+0.123	+7.930	<.001	.008	3	1
LUAD	MBD3L4 →	+0.064	+7.930	<.001	.008	3	1
LUAD	MIR495 →	+0.371	+7.930	<.001	.008	3	1
LUAD	MIR764 →	+0.448	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

SNORD114-28 survival (RNA) · tumor vs normal (RNA) · all SNORD114-28 data types