Across TCGA patient cohorts, SNORD114-25 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORD114-25-associated genes across cancer lineages are MIR7976, RN7SL134P, and MIR4265. Each is linked with SNORD114-25 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD114-25-to-partner and partner-to-SNORD114-25 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD114-25→partner) and Y-score (partner→SNORD114-25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7976 →	+0.707	+4.038	<.001	.004	3	1
UCEC	RN7SL134P →	+0.247	+4.184	<.001	.003	3	1
UCEC	MIR4265 →	+0.577	+4.997	<.001	.003	3	1
UCEC	RPL34P36 →	+0.120	+4.538	.002	.006	3	1
UCEC	MIR31 →	+0.663	+4.267	<.001	.009	3	1
UCEC	TRAJ21 →	+0.778	+3.936	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

SNORD114-25 survival (RNA) · tumor vs normal (RNA) · all SNORD114-25 data types