Q-omics provides the consensus-scored MIR31 profile across patient tissues and cancer cell-line models. MIR31 expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in READ. Among the 18 cancer types available for tumor–normal comparison, MIR31 is differentially expressed in 3, with the highest sampling consensus in THCA. Additionally, MIR31 RNA expression shows 5,894 significant gene co-expression associations, with the highest sampling consensus in LUAD. Together, these results highlight READ, THCA, and LUAD as cancer lineages where MIR31 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR31 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR31 survival associations across molecular data types. MIR31 RNA expression shows survival associations in the most cancer types (12), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR31 RNA expression–survival associations across cancer types. High MIR31 expression shows unfavorable associations in READ, MESO, SKCM, LUAD, SARC and UCEC. The READ Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify READ as the clearest survival context for MIR31 RNA expression.
This table summarizes MIR31 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for MIR31. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR31 shows lower tumor expression in KIRC and higher tumor expression in THCA and LUAD. The THCA box plot shows higher MIR31 RNA expression in tumor versus normal tissue (log2 FC = +0.201, t-test p = .037).
This table shows molecular features associated with MIR31 in patient tissues and cancer cell lines. In patient samples, MIR31 shows the broadest associations at the RNA and protein expression levels, with LUAD recurring as the lineage with the largest associated feature set.
