Across TCGA patient cohorts, SNORD114-2 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD114-2-associated genes across cancer lineages are MTND1P33, RPL27P12, and RN7SL679P. Each is linked with SNORD114-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD114-2-to-partner and partner-to-SNORD114-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD114-2→partner) and Y-score (partner→SNORD114-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MTND1P33 →	+0.044	+5.039	<.001	.003	3	1
SKCM	RPL27P12 →	+0.084	+4.208	<.001	.003	3	1
SKCM	RN7SL679P →	+0.188	+3.838	<.001	.006	3	1
SKCM	RPL34P21 →	+0.200	+5.043	<.001	<.001	3	1
SKCM	CHORDC1P3 →	+0.014	+4.385	.003	.008	3	1
SKCM	CCDC34P1 →	+0.069	+4.614	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

SNORD114-2 survival (RNA) · tumor vs normal (RNA) · all SNORD114-2 data types