Across TCGA pan-cancer cohorts, SNORD114-2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of SNORD114-2’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where SNORD114-2 RNA is repressed in tumor relative to normal tissue. In most cancer types SNORD114-2 is over-expressed in tumor, although a few such as BLCA show the opposite, repressed pattern.

BLCA are the cancer types where SNORD114-2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORD114-2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	−0.196	.040	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: SNORD114-2 RNA expression & survival · all SNORD114-2 data types