Across TCGA patient cohorts, SNORD113-4 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SNORD113-4-associated genes across cancer lineages are UBE2V1P10, RNU6-1328P, and PRAMEF32P. Each is linked with SNORD113-4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD113-4-to-partner and partner-to-SNORD113-4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD113-4→partner) and Y-score (partner→SNORD113-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UBE2V1P10 →	+0.154	+8.066	<.001	.007	3	2
HNSC	RNU6-1328P →	+0.293	+7.954	<.001	.008	3	1
HNSC	PRAMEF32P →	+0.034	+7.954	<.001	.008	3	1
HNSC	TSPY18P →	+0.069	+7.954	<.001	.008	3	1
HNSC	MIR4693 →	+0.388	+7.954	<.001	.008	3	1
HNSC	MIR4276 →	+0.413	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

SNORD113-4 survival (RNA) · tumor vs normal (RNA) · all SNORD113-4 data types