Across TCGA patient cohorts, SNORA53 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,322 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SNORA53-associated proteins across cancer lineages are BRD7, BRD8, and CCAR1. Each is linked with SNORA53 in more than 3 cancer types. Because this analysis shows association rather than direction, both SNORA53-to-partner and partner-to-SNORA53 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORA53→partner) and Y-score (partner→SNORA53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BRD7 →	+0.316	+0.523	<.001	.003	3	4
LSCC	BRD8 →	+0.247	+0.668	.001	<.001	3	3
GBM	CCAR1 →	+0.161	+0.552	.002	<.001	3	3
GBM	CCDC86 →	+0.319	+0.620	<.001	<.001	3	3
LUAD	CDK9 →	+0.233	+0.595	<.001	.001	3	3
LSCC	CPSF6 →	+0.291	+0.839	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,322 associations by consensus.

Exploration

SNORA53 survival (RNA) · tumor vs normal (RNA) · all SNORA53 data types