SNIP1

Across TCGA patient cohorts, SNIP1 mutation is significantly associated with the RNA expression of many other genes, with 2,426 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNIP1-associated genes across cancer lineages are KLRD1, CCL5, and TAF9. Each is linked with SNIP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNIP1-to-partner and partner-to-SNIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KLRD1 grouped by SNIP1-low versus SNIP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNIP1→partner) and Y-score (partner→SNIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KLRD1 →	+0.343	+2.736	<.001	<.001	3	3
UCEC	CCL5 →	+1.090	+3.716	.001	<.001	3	2
UCEC	TAF9 →	+0.774	+4.021	<.001	<.001	3	2
UCEC	RN7SL248P →	+0.051	+2.985	<.001	.006	3	2
UCEC	TUBGCP5 →	+0.407	+1.880	.002	.005	3	2
BLCA	MIR5007 →	+0.565	+5.147	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,426 associations by consensus.

KLRD1 by SNIP1 expression — UCEC

Explore this box plot interactively →