SNIP1

Across TCGA pan-cancer cohorts, SNIP1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of SNIP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SNIP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNIP1 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

HNSC, THCA, and KICH are the cancer types where SNIP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNIP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.510	<.001	10	view →
THCA	Male	All	−0.475	<.001	9	view →
KICH	Female	All	−0.959	<.001	8	view →
STAD	All	II,III,IV	+0.423	.005	4	view →
KIRC	All	All	+0.254	<.001	3	view →
CHOL	Male	All	+1.138	<.001	2	view →
UCEC	All	All	−0.389	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

SNIP1–HNSC

Open the HNSC breakdown →