SND1-IT1

Across TCGA pan-cancer cohorts, SND1-IT1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated SND1-IT1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SND1-IT1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SND1-IT1 expression acts as an unfavorable survival marker, although some lineages such as CESC and LGG show a favorable association.

ACC, BLCA, and KIRC are the cancer types where SND1-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Quartile	All	0.393	0.698	.001	68	view →
BLCA	OS	Tertile	All	0.364	0.679	.001	66	view →
KIRC	OS	Median	All	0.560	0.690	<.001	50	view →
LIHC	OS	Tertile	All	0.350	0.616	.001	50	view →
CESC	OS	Median	III,IV	0.872	0.599	.002	42	view →
LGG	OS	Median	All	0.941	0.848	<.001	37	view →
THYM	DFS	Median	All	0.617	0.943	.005	36	view →
KIRP	DFS	Median	II,III,IV	0.617	0.850	.008	31	view →
LUSC	OS	Tertile	II,III,IV	0.846	0.640	.002	29	view →
LAML	DFS	Tertile	All	0.508	0.219	.025	14	view →
UCS	DFS	Tertile	IV	0.978	0.490	.024	12	view →
PAAD	DFS	Tertile	II,III,IV	0.289	0.502	.007	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

SND1-IT1–ACC (DFS)

Open the ACC breakdown →