SNCAIP

Across TCGA patient cohorts, SNCAIP mutation is significantly associated with the RNA expression of many other genes, with 3,898 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNCAIP-associated genes across cancer lineages are SRP19, BUB3, and TYW3. Each is linked with SNCAIP in more than 4 cancer types. Because this analysis shows association rather than direction, both SNCAIP-to-partner and partner-to-SNCAIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SRP19 grouped by SNCAIP-low versus SNCAIP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNCAIP→partner) and Y-score (partner→SNCAIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SRP19 →	+0.372	+2.191	<.001	.001	3	4
UCEC	BUB3 →	+0.380	+1.534	<.001	.005	3	4
UCEC	TYW3 →	+0.358	+2.706	<.001	<.001	3	4
UCEC	ZNF367 →	+0.548	+1.415	<.001	.002	3	4
UCEC	MORN4 →	+0.293	+1.499	.007	.007	3	4
UCEC	PSMA4 →	+0.371	+1.797	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,898 associations by consensus.

SRP19 by SNCAIP expression — UCEC

Explore this box plot interactively →