SNCAIP

Across TCGA pan-cancer cohorts, SNCAIP RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of SNCAIP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SNCAIP RNA is repressed in tumor relative to normal tissue. In most cancer types SNCAIP is over-expressed in tumor, although a few such as KIRC and UCEC show the opposite, repressed pattern.

KIRC, HNSC, and UCEC are the cancer types where SNCAIP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNCAIP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−0.706	<.001	12	view →
HNSC	Male	All	+0.933	<.001	8	view →
UCEC	All	All	−1.944	<.001	6	view →
BRCA	All	II,III,IV	−0.934	<.001	6	view →
LIHC	All	All	+0.264	.001	6	view →
KIRP	All	All	−0.711	<.001	5	view →
LUAD	Female	II,III,IV	−0.692	<.001	5	view →
THCA	Male	II,III,IV	−0.471	.014	3	view →
PAAD	Female	All	−0.779	.034	2	view →
PRAD	All	All	−0.329	.023	2	view →
LUSC	Male	III,IV	−0.897	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

SNCAIP–KIRC

Open the KIRC breakdown →