SNCAIP

Across TCGA cell cohorts, SNCAIP mutation is significantly associated with the RNA expression of many other genes, with 192 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNCAIP-associated genes across cancer lineages are LIPK, IFNA13, and MAGEB5. Each is linked with SNCAIP in more than 1 cancer types. Because this analysis shows association rather than direction, both SNCAIP-to-partner and partner-to-SNCAIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LIPK grouped by SNCAIP-low versus SNCAIP-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNCAIP→partner) and Y-score (partner→SNCAIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	LIPK →	+0.032	+4.930	<.001	.008	3	1
SOFT_TISSUE	IFNA13 →	+0.072	+4.930	<.001	.008	3	1
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
SKIN	WARS1 →	-1.029	-3.321	<.001	.003	3	1
SKIN	CXCR5 →	+0.280	+2.121	.002	.009	3	1
SKIN	ASB18 →	+0.047	+2.125	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 192 associations by consensus.

LIPK by SNCAIP expression — SOFT_TISSUE

Explore this box plot interactively →