SNAI2

Across TCGA patient cohorts, SNAI2 mutation is significantly associated with the RNA expression of many other genes, with 1,102 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNAI2-associated genes across cancer lineages are RNU6-1068P, MIR194-1, and RNU6-680P. Each is linked with SNAI2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNAI2-to-partner and partner-to-SNAI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1068P grouped by SNAI2-low versus SNAI2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAI2→partner) and Y-score (partner→SNAI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1068P →	+0.407	+4.602	<.001	.008	3	2
UCEC	MIR194-1 →	+0.424	+2.112	.002	.004	3	2
COAD	RNU6-680P →	+0.514	+4.681	.008	.003	3	1
COAD	ZNF736P7Y →	+0.087	+5.251	<.001	.003	3	1
COAD	LINC01173 →	+0.152	+4.602	<.001	.008	3	1
BLCA	RPSAP27 →	+0.076	+4.605	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,102 associations by consensus.

RNU6-1068P by SNAI2 expression — COAD

Explore this box plot interactively →