SNAI2

Across TCGA cell cohorts, SNAI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,347 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SNAI2-associated GO terms across cancer lineages are Cell migration involved in endocardial cushion formation, Regulation of vitamin D biosynthetic process, and Amino acid metabolic process. Each is linked with SNAI2 in more than 13 cancer types. Because this analysis shows association rather than direction, both SNAI2-to-partner and partner-to-SNAI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell migration involved in endocardial cushion formation grouped by SNAI2-low versus SNAI2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNAI2→partner) and Y-score (partner→SNAI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cell migration involved in endocardial cushion formation →	+1.383	+2.905	<.001	.001	3	14
BONE	Regulation of vitamin D biosynthetic process →	+1.563	+3.278	<.001	<.001	3	12
LIVER	Amino acid metabolic process →	-0.089	-3.832	<.001	<.001	3	12
PANCREAS	Blood coagulation, fibrin clot formation →	+0.339	+2.855	<.001	<.001	3	12
LIVER	Pyrimidine-containing compound transmembrane transport →	-0.223	-3.022	<.001	<.001	3	12
BONE	Negative regulation of vitamin D biosynthetic process →	+1.428	+3.369	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,347 associations by consensus.

Cell migration involved in endocardial cushion formation by SNAI2 expression — OESOPHAGUS

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