Across TCGA patient cohorts, SMYD3 protein abundance is significantly associated with the RNA expression of many other genes, with 13,650 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMYD3-associated genes across cancer lineages are SMYD3-AS1, RNU6-1283P, and GNPAT. Each is linked with SMYD3 in more than 6 cancer types. Because this analysis shows association rather than direction, both SMYD3-to-partner and partner-to-SMYD3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMYD3→partner) and Y-score (partner→SMYD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SMYD3-AS1 →	+0.970	+0.492	<.001	<.001	3	7
HNSC	RNU6-1283P →	+1.230	+0.415	<.001	<.001	3	7
HNSC	GNPAT →	+0.625	+0.335	.004	.001	3	6
BRCA	COG2 →	+0.641	+0.539	<.001	<.001	3	6
UCEC	NTPCR →	+0.639	+0.401	<.001	<.001	2	7
LSCC	HNRNPU →	+0.470	+0.331	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,650 associations by consensus.

Exploration

SMYD3 survival (RNA) · tumor vs normal (RNA) · all SMYD3 data types