SMOX

Across TCGA patient cohorts, SMOX protein abundance is significantly associated with the RNA expression of many other genes, with 1,196 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMOX-associated genes across cancer lineages are VASH1, CCT5P1, and CRYM. Each is linked with SMOX in more than 1 cancer types. Because this analysis shows association rather than direction, both SMOX-to-partner and partner-to-SMOX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMOX versus VASH1 in HNSC, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMOX→partner) and Y-score (partner→SMOX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VASH1 →	-1.051	-0.490	.002	.001	3	2
GBM	CCT5P1 →	+0.721	+0.388	<.001	.004	3	2
UCEC	CRYM →	+1.577	+1.417	.005	.008	3	1
UCEC	ISYNA1 →	+1.075	+1.056	.007	.006	3	1
UCEC	PDLIM1 →	+1.087	+1.294	.006	.003	3	1
UCEC	TWNK →	+0.944	+1.405	.006	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,196 associations by consensus.

SMOX vs VASH1 — HNSC

Explore this scatter interactively →