SMOX

Across TCGA cell cohorts, SMOX RNA expression is significantly associated with the go_rna of many other GO terms, with 4,781 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SMOX-associated GO terms across cancer lineages are Regulation of cell-substrate adhesion, Polyamine catabolic process, and Positive regulation of cell-substrate adhesion. Each is linked with SMOX in more than 11 cancer types. Because this analysis shows association rather than direction, both SMOX-to-partner and partner-to-SMOX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell-substrate adhesion grouped by SMOX-low versus SMOX-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMOX→partner) and Y-score (partner→SMOX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of cell-substrate adhesion →	+0.075	+1.499	<.001	.001	3	12
LUNG_NSCLC_LUAD	Polyamine catabolic process →	+0.248	+2.067	<.001	<.001	3	11
BREAST	Positive regulation of cell-substrate adhesion →	+0.109	+2.039	<.001	<.001	3	11
LARGE_INTESTINE	Positive regulation of protein localization to endoplasmic reticulum →	+0.095	+1.397	<.001	<.001	3	11
OVARY	Negative regulation of protein maturation →	+0.194	+1.866	<.001	<.001	3	10
BONE	Regulation of protein localization to endoplasmic reticulum →	+0.096	+0.961	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,781 associations by consensus.

Regulation of cell-substrate adhesion by SMOX expression — SOFT_TISSUE

Explore this box plot interactively →