Across TCGA pan-cancer cohorts, SMIM7P1 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated SMIM7P1 data layer.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SMIM7P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SMIM7P1 expression acts as an unfavorable survival marker, although some lineages such as LGG and SKCM show a favorable association.
HNSC, LIHC, and OV are the cancer types where SMIM7P1 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.