Across TCGA pan-cancer cohorts, SMIM7P1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of SMIM7P1’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where SMIM7P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SMIM7P1 is over-expressed in tumor.
COAD are the cancer types where SMIM7P1 tumor–normal differential expression is most reproducible.