Q-omics provides the consensus-scored SMIM7P1 profile across patient tissues and cancer cell-line models. SMIM7P1 expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, SMIM7P1 is differentially expressed in 1, with the highest sampling consensus in COAD. Additionally, SMIM7P1 RNA expression shows 6,833 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight HNSC, COAD, and GBM as cancer lineages where SMIM7P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SMIM7P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SMIM7P1 survival associations across molecular data types. SMIM7P1 RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SMIM7P1 RNA expression–survival associations across cancer types. High SMIM7P1 expression shows unfavorable associations in HNSC, LIHC, BLCA, OV, KIRC and UCEC. The HNSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for SMIM7P1 RNA expression.
This table summarizes SMIM7P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for SMIM7P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SMIM7P1 shows higher tumor expression in COAD. The COAD box plot shows higher SMIM7P1 RNA expression in tumor versus normal tissue (log2 FC = +0.093, t-test p = .049).
This table shows molecular features associated with SMIM7P1 in patient tissues and cancer cell lines. In patient samples, SMIM7P1 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
