SMIM28

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SMIM28 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,403 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMIM28-associated proteins across cancer lineages are ZNF326, NHSL1, and NHSL1_S328. Each is linked with SMIM28 in more than 2 cancer types. Because this analysis shows association rather than direction, both SMIM28-to-partner and partner-to-SMIM28 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM28 versus ZNF326 in HNSC, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM28→partner) and Y-score (partner→SMIM28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCZNF326 →+0.314+0.307.002.00933
LSCCNHSL1 →+0.330+0.092<.001<.00133
LSCCNHSL1_S328 →+0.801+0.080<.001<.00133
UCECARHGAP17 →-0.167-0.750.003<.00133
BRCAFADS2 →+0.785+0.045<.001<.00133
GBMFMNL1 →-0.411-0.205<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,403 associations by consensus.

SMIM28 vs ZNF326 — HNSC

Per-sample scatter of SMIM28 vs ZNF326 in HNSC (Pearson r = 0.28).

Explore this scatter interactively →

Exploration