SMIM28

Across TCGA cell cohorts, SMIM28 RNA expression is significantly associated with the go_rna of many other GO terms, with 379 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SMIM28-associated GO terms across cancer lineages are Alcohol biosynthetic process, Positive regulation of nitric-oxide synthase activity, and Nephron morphogenesis. Each is linked with SMIM28 in more than 3 cancer types. Because this analysis shows association rather than direction, both SMIM28-to-partner and partner-to-SMIM28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alcohol biosynthetic process grouped by SMIM28-low versus SMIM28-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM28→partner) and Y-score (partner→SMIM28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Alcohol biosynthetic process →	+0.072	+0.641	.001	<.001	2	4
LUNG_SCLC	Positive regulation of nitric-oxide synthase activity →	+0.844	+0.807	<.001	.001	3	3
STOMACH	Nephron morphogenesis →	+0.093	+0.015	.001	.004	3	2
STOMACH	Nephron tubule morphogenesis →	+0.096	+0.015	.001	.004	3	2
STOMACH	Nephron epithelium morphogenesis →	+0.093	+0.015	.001	.004	3	2
LUNG_SCLC	Exocytosis →	+0.053	+0.924	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 379 associations by consensus.

Alcohol biosynthetic process by SMIM28 expression — LUNG_SCLC

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