SMIM24

Across TCGA patient cohorts, SMIM24 protein abundance is significantly associated with the RNA expression of many other genes, with 7,535 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMIM24-associated genes across cancer lineages are KRT8P3, SLC5A11, and MLXIPL. Each is linked with SMIM24 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM24-to-partner and partner-to-SMIM24 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM24 versus KRT8P3 in HNSC, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM24→partner) and Y-score (partner→SMIM24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KRT8P3 →	-1.105	-0.644	.006	.005	3	2
GBM	SLC5A11 →	+2.448	+1.635	.001	.001	3	2
CCRCC	MLXIPL →	+0.999	+0.606	<.001	<.001	3	2
CCRCC	MIR124-1HG →	+0.147	+0.647	.004	<.001	3	2
COAD	FAM32A →	-0.500	-0.741	.002	.005	3	1
COAD	SHC2 →	+1.750	+0.911	.008	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,535 associations by consensus.

SMIM24 vs KRT8P3 — HNSC

Explore this scatter interactively →