SMIM24

Across TCGA patient cohorts, SMIM24 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMIM24-associated genes across cancer lineages are LINC01173, RN7SL713P, and MIR3136. Each is linked with SMIM24 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM24-to-partner and partner-to-SMIM24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01173 grouped by SMIM24-low versus SMIM24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM24→partner) and Y-score (partner→SMIM24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01173 →	+0.420	+2.847	<.001	.004	3	1
UCEC	RN7SL713P →	+0.133	+3.694	<.001	.003	3	1
UCEC	MIR3136 →	+0.832	+3.184	<.001	.001	3	1
UCEC	SNORA74C-1 →	+0.382	+2.993	.002	.003	3	1
UCEC	RPL14P6 →	+0.266	+2.847	<.001	.004	3	1
UCEC	RNU6-598P →	+0.219	+3.242	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

LINC01173 by SMIM24 expression — UCEC

Explore this box plot interactively →