SMIM24

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SMIM24 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SMIM24-associated genes across cancer lineages are lymphatic Endothelial cells and mv Endothelial cells. Each is linked with SMIM24 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM24-to-partner and partner-to-SMIM24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, lymphatic Endothelial cells grouped by SMIM24-low versus SMIM24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM24→partner) and Y-score (partner→SMIM24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEClymphatic Endothelial cells →-0.028-2.959.044.03621
UCECmv Endothelial cells →-0.036-2.989.009.03721
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

lymphatic Endothelial cells by SMIM24 expression — UCEC

Box plot of lymphatic Endothelial cells in SMIM24-low vs SMIM24-high samples in UCEC.

Explore this box plot interactively →

Exploration