SMIM20

Across TCGA patient cohorts, SMIM20 protein abundance is significantly associated with the RNA expression of many other genes, with 8,713 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SMIM20-associated genes across cancer lineages are GRPEL1, CRISPLD2, and ELL. Each is linked with SMIM20 in more than 3 cancer types. Because this analysis shows association rather than direction, both SMIM20-to-partner and partner-to-SMIM20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM20 versus GRPEL1 in OV, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM20→partner) and Y-score (partner→SMIM20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GRPEL1 →	+0.538	+0.391	.003	.003	3	4
OV	CRISPLD2 →	-0.949	-0.350	.002	.001	3	3
OV	ELL →	-0.386	-0.319	.001	.003	3	3
OV	AEBP1 →	-1.511	-0.327	<.001	.002	3	3
OV	SF3B4 →	-0.704	-0.454	.004	.008	3	3
COAD	PPP1R18 →	-0.710	-0.256	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,713 associations by consensus.

SMIM20 vs GRPEL1 — OV

Explore this scatter interactively →