SMIM15P1

Across TCGA patient cohorts, SMIM15P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,700 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SMIM15P1-associated GO terms across cancer lineages are Protein stabilization, Regulation of binding, and Negative regulation of NF-kappaB transcription factor activity. Each is linked with SMIM15P1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SMIM15P1-to-partner and partner-to-SMIM15P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein stabilization grouped by SMIM15P1-low versus SMIM15P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM15P1→partner) and Y-score (partner→SMIM15P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein stabilization →	+0.099	+0.122	<.001	<.001	3	8
STAD	Regulation of binding →	+0.095	+0.113	<.001	<.001	3	8
STAD	Negative regulation of NF-kappaB transcription factor activity →	+0.076	+0.136	<.001	<.001	3	8
STAD	Response to hydrogen peroxide →	+0.099	+0.125	<.001	<.001	3	8
STAD	Negative regulation of DNA-binding transcription factor activity →	+0.074	+0.123	<.001	<.001	3	8
STAD	Regulation of DNA biosynthetic process →	+0.100	+0.112	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,700 associations by consensus.

Protein stabilization by SMIM15P1 expression — STAD

Explore this box plot interactively →