SMIM15P1

Across TCGA pan-cancer cohorts, SMIM15P1 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated SMIM15P1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SMIM15P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SMIM15P1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LUAD show a favorable association.

KIRC, BRCA, and BLCA are the cancer types where SMIM15P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.175	0.624	.005	54	view →
BRCA	OS	Tertile	IV	0.282	0.820	.012	36	view →
BLCA	DFS	Tertile	All	0.341	0.532	.012	18	view →
SKCM	DFS	Tertile	III,IV	0.901	0.591	.014	9	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
LUAD	DFS	Tertile	All	0.950	0.781	.039	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SMIM15P1–KIRC (DFS)

Open the KIRC breakdown →