SMIM14

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SMIM14 protein abundance is significantly associated with the RNA expression of many other genes, with 59 significant associations in total. OV shows the largest number of these associations.

The most reproducible SMIM14-associated genes across cancer lineages are ANKRD54, OSCP1, and MYB. Each is linked with SMIM14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM14-to-partner and partner-to-SMIM14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM14 versus ANKRD54 in OV, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM14→partner) and Y-score (partner→SMIM14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVANKRD54 →+0.927+1.488.008.00531
OVOSCP1 →+1.559+1.250.001.00131
OVMYB →+2.210+1.600<.001.00331
OVMGAT3 →+1.602+1.574.008.00431
OVMAP7 →+1.089+1.208.001.00831
OVAK7 →+3.137+1.837.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

SMIM14 vs ANKRD54 — OV

Per-sample scatter of SMIM14 vs ANKRD54 in OV (Pearson r = 0.67).

Explore this scatter interactively →

Exploration