SMIM14

Across TCGA patient cohorts, SMIM14 protein abundance is significantly associated with the protein abundance of many other proteins, with 80 significant associations in total. OV shows the largest number of these associations.

The most reproducible SMIM14-associated proteins across cancer lineages are SRRM2_S876, TP53BP1_S1317, and VPS18. Each is linked with SMIM14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMIM14-to-partner and partner-to-SMIM14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM14 versus SRRM2_S876 in OV, with a Pearson correlation of -0.69.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM14→partner) and Y-score (partner→SMIM14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SRRM2_S876 →	-0.647	-1.216	.001	.002	3	1
OV	TP53BP1_S1317 →	-0.997	-1.987	<.001	.002	3	1
OV	VPS18 →	-0.208	-1.264	<.001	.001	3	1
OV	B4GAT1 →	+0.557	+1.742	.001	.003	3	1
OV	DEAF1 →	+0.560	+1.173	.002	.003	3	1
OV	SURF1 →	+0.358	+1.285	<.001	<.001	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 80 associations by consensus.

SMIM14 vs SRRM2_S876 — OV

Explore this scatter interactively →