SMIM14

Across TCGA cell cohorts, SMIM14 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,576 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SMIM14-associated GO terms across cancer lineages are Vesicle budding from membrane, Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and Macroautophagy. Each is linked with SMIM14 in more than 14 cancer types. Because this analysis shows association rather than direction, both SMIM14-to-partner and partner-to-SMIM14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle budding from membrane grouped by SMIM14-low versus SMIM14-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM14→partner) and Y-score (partner→SMIM14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Vesicle budding from membrane →	+0.076	+1.942	.003	.003	3	15
URINARY_TRACT	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.096	-1.607	<.001	<.001	3	14
PANCREAS	Macroautophagy →	+0.057	+1.767	<.001	<.001	3	14
BONE	Nucleolar large rRNA transcription by RNA polymerase I →	-0.148	-1.860	<.001	<.001	3	13
LARGE_INTESTINE	Endoplasmic reticulum to cytosol transport →	+0.120	+1.177	<.001	.002	3	13
BONE	Endoplasmic reticulum unfolded protein response →	+0.101	+0.904	.003	.009	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,576 associations by consensus.

Vesicle budding from membrane by SMIM14 expression — LUNG_NSCLC_LUSC

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