SMIM11B

Across TCGA cell cohorts, SMIM11B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,814 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SMIM11B-associated GO terms across cancer lineages are Positive regulation of response to cytokine stimulus, Regulation of receptor clustering, and Cerebral cortex radially oriented cell migration. Each is linked with SMIM11B in more than 6 cancer types. Because this analysis shows association rather than direction, both SMIM11B-to-partner and partner-to-SMIM11B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of response to cytokine stimulus grouped by SMIM11B-low versus SMIM11B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM11B→partner) and Y-score (partner→SMIM11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of response to cytokine stimulus →	-0.103	-1.116	<.001	.001	3	7
BONE	Regulation of receptor clustering →	-0.131	-0.953	<.001	<.001	3	6
SKIN	Cerebral cortex radially oriented cell migration →	-0.089	-0.803	<.001	<.001	3	6
LARGE_INTESTINE	Mitochondrial transcription →	+0.073	+0.870	<.001	<.001	3	6
LUNG_NSCLC_LUAD	Negative regulation of response to biotic stimulus →	-0.074	-0.875	<.001	.003	3	6
LARGE_INTESTINE	Nuclear-transcribed mRNA catabolic process, deadenylation-independent decay →	-0.075	-0.853	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,814 associations by consensus.

Positive regulation of response to cytokine stimulus by SMIM11B expression — URINARY_TRACT

Explore this box plot interactively →