Across TCGA cell cohorts, SMIM11A protein abundance is significantly associated with the RNA expression of many other genes, with 1,880 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SMIM11A-associated genes across cancer lineages are NPRL3, SHMT2, and MLST8. Each is linked with SMIM11A in more than 5 cancer types. Because this analysis shows association rather than direction, both SMIM11A-to-partner and partner-to-SMIM11A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM11A→partner) and Y-score (partner→SMIM11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	NPRL3 →	-0.752	-0.901	.001	.005	3	6
LIVER	SHMT2 →	-1.062	-1.196	.003	.007	3	5
CNS	MLST8 →	-0.560	-0.881	.002	.002	3	5
BONE	RPP25 →	-2.174	-1.490	.002	.008	3	4
BONE	RNF208 →	-2.780	-1.627	.001	.009	3	4
BONE	FOXD1 →	+3.750	+1.932	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,880 associations by consensus.

Exploration

SMIM11A survival (RNA) · tumor vs normal (RNA) · all SMIM11A data types