SMIM10L2A

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SMIM10L2A RNA expression is significantly associated with the protein abundance of many other proteins, with 15,866 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMIM10L2A-associated proteins across cancer lineages are GSTM2, GSTM3, and TRIM2. Each is linked with SMIM10L2A in more than 4 cancer types. Because this analysis shows association rather than direction, both SMIM10L2A-to-partner and partner-to-SMIM10L2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMIM10L2A versus GSTM2 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM10L2A→partner) and Y-score (partner→SMIM10L2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCGSTM2 →+0.848+0.667.001<.00135
LSCCGSTM3 →+0.958+0.739.001<.00135
HNSCTRIM2 →+0.632+0.512<.001<.00135
UCECTRAF3IP2 →-0.314-0.585.007.00234
BRCAVAV3 →-0.353-0.744<.001<.00134
LSCCCTPS2 →+0.316+0.863<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,866 associations by consensus.

SMIM10L2A vs GSTM2 — HNSC

Per-sample scatter of SMIM10L2A vs GSTM2 in HNSC (Pearson r = 0.34).

Explore this scatter interactively →

Exploration