SMIM10L2A

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SMIM10L2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,064 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SMIM10L2A-associated GO terms across cancer lineages are Regulation of myoblast fusion, Mitochondrial electron transport, cytochrome c to oxygen, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with SMIM10L2A in more than 13 cancer types. Because this analysis shows association rather than direction, both SMIM10L2A-to-partner and partner-to-SMIM10L2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by SMIM10L2A-low versus SMIM10L2A-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMIM10L2A→partner) and Y-score (partner→SMIM10L2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHRegulation of myoblast fusion →+0.143+0.695<.001<.001314
OESOPHAGUSMitochondrial electron transport, cytochrome c to oxygen →+0.169+0.886<.001<.001313
STOMACHNegative regulation of syncytium formation by plasma membrane fusion →+0.159+0.606<.001.003312
SKINRegulation of macroautophagy →+0.054+0.283<.001<.001312
STOMACHCytoplasmic translation →+0.080+0.431.001.008312
STOMACHRegulation of syncytium formation by plasma membrane fusion →+0.135+0.671<.001.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,064 associations by consensus.

Regulation of myoblast fusion by SMIM10L2A expression — STOMACH

Box plot of Regulation of myoblast fusion in SMIM10L2A-low vs SMIM10L2A-high samples in STOMACH.

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