SMG6-IT1

Across TCGA patient cohorts, SMG6-IT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,327 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SMG6-IT1-associated GO terms across cancer lineages are Golgi organization, Protein K63-linked ubiquitination, and Negative regulation of cellular catabolic process. Each is linked with SMG6-IT1 in more than 16 cancer types. Because this analysis shows association rather than direction, both SMG6-IT1-to-partner and partner-to-SMG6-IT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi organization grouped by SMG6-IT1-low versus SMG6-IT1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SMG6-IT1→partner) and Y-score (partner→SMG6-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Golgi organization →	+0.051	+0.226	<.001	<.001	3	16
DLBC	Protein K63-linked ubiquitination →	+0.070	+0.090	.001	.006	2	17
STAD	Negative regulation of cellular catabolic process →	+0.050	+0.282	<.001	<.001	3	16
DLBC	Glycerolipid biosynthetic process →	+0.062	+0.067	<.001	.005	2	16
STAD	Protein targeting to vacuole →	+0.055	+0.223	<.001	<.001	3	15
STAD	Vacuole organization →	+0.053	+0.279	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,327 associations by consensus.

Golgi organization by SMG6-IT1 expression — STAD

Explore this box plot interactively →