SMARCA5-AS1

Across TCGA patient cohorts, SMARCA5-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,188 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SMARCA5-AS1-associated proteins across cancer lineages are PIK3CG_S974, GAB1_S419, and CASP10. Each is linked with SMARCA5-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SMARCA5-AS1-to-partner and partner-to-SMARCA5-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMARCA5-AS1 versus PIK3CG_S974 in GBM, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMARCA5-AS1→partner) and Y-score (partner→SMARCA5-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PIK3CG_S974 →	-0.626	-0.486	<.001	<.001	3	4
LUAD	GAB1_S419 →	+0.581	+0.375	.002	.002	3	4
GBM	CASP10 →	-0.451	-0.538	<.001	<.001	3	4
HNSC	TRIM2 →	+0.747	+0.558	<.001	<.001	3	4
LUAD	RAP1GAP →	+0.631	+0.461	.005	<.001	3	4
LUAD	OXNAD1 →	-0.430	-0.451	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,188 associations by consensus.

SMARCA5-AS1 vs PIK3CG_S974 — GBM

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