SLX1A

Across TCGA patient cohorts, SLX1A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,323 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible SLX1A-associated GO terms across cancer lineages are Base-excision repair, AP site formation, Regulation of DNA-directed DNA polymerase activity, and Positive regulation of DNA repair. Each is linked with SLX1A in more than 18 cancer types. Because this analysis shows association rather than direction, both SLX1A-to-partner and partner-to-SLX1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Base-excision repair, AP site formation grouped by SLX1A-low versus SLX1A-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLX1A→partner) and Y-score (partner→SLX1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Base-excision repair, AP site formation →	+0.057	+0.090	<.001	<.001	3	19
STAD	Regulation of DNA-directed DNA polymerase activity →	+0.088	+0.097	<.001	<.001	3	18
STAD	Positive regulation of DNA repair →	+0.069	+0.078	<.001	<.001	3	18
STAD	Base-excision repair, gap-filling →	+0.063	+0.070	<.001	<.001	3	18
STAD	Base-excision repair →	+0.073	+0.074	<.001	<.001	3	17
STAD	Mitotic intra-S DNA damage checkpoint signaling →	+0.058	+0.079	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,323 associations by consensus.

Base-excision repair, AP site formation by SLX1A expression — STAD

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