SLX1A

Across TCGA cell cohorts, SLX1A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,474 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SLX1A-associated GO terms across cancer lineages are Positive regulation of t-circle formation, Regulation of t-circle formation, and Negative regulation of inflammasome-mediated signaling pathway. Each is linked with SLX1A in more than 17 cancer types. Because this analysis shows association rather than direction, both SLX1A-to-partner and partner-to-SLX1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of t-circle formation grouped by SLX1A-low versus SLX1A-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLX1A→partner) and Y-score (partner→SLX1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of t-circle formation →	+0.229	+1.735	<.001	<.001	3	18
BONE	Regulation of t-circle formation →	+0.123	+1.454	<.001	<.001	3	16
BONE	Negative regulation of inflammasome-mediated signaling pathway →	+0.152	+2.021	<.001	<.001	3	10
BONE	Peptidyl-methionine modification →	+0.239	+1.842	<.001	<.001	3	10
URINARY_TRACT	Positive regulation of sphingolipid biosynthetic process →	+0.150	+1.342	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of endoplasmic reticulum tubular network organization →	-0.076	-0.879	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,474 associations by consensus.

Positive regulation of t-circle formation by SLX1A expression — STOMACH

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