SLMAP

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLMAP protein abundance is significantly associated with the RNA expression of many other genes, with 9,794 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SLMAP-associated genes across cancer lineages are MYH11, ACTG2, and LMOD1. Each is linked with SLMAP in more than 6 cancer types. Because this analysis shows association rather than direction, both SLMAP-to-partner and partner-to-SLMAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLMAP versus MYH11 in COAD, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLMAP→partner) and Y-score (partner→SLMAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADMYH11 →+2.021+0.796<.001<.00137
UCECACTG2 →+2.015+0.400<.001<.00127
COADLMOD1 →+1.496+0.792<.001<.00136
COADSYNPO2 →+1.548+0.866<.001<.00136
COADDES →+3.637+0.925<.001<.00136
COADPLN →+1.712+0.670<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,794 associations by consensus.

SLMAP vs MYH11 — COAD

Per-sample scatter of SLMAP vs MYH11 in COAD (Pearson r = 0.63).

Explore this scatter interactively →

Exploration