SLMAP

Across TCGA pan-cancer cohorts, SLMAP RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of SLMAP’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where SLMAP RNA is repressed in tumor relative to normal tissue. In most cancer types SLMAP is over-expressed in tumor, although a few such as BLCA and THCA show the opposite, repressed pattern.

BLCA, THCA, and KIRC are the cancer types where SLMAP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLMAP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	III,IV	−1.899	<.001	11	view →
THCA	Male	III,IV	−1.430	<.001	11	view →
KIRC	Male	II,III,IV	−0.810	<.001	11	view →
COAD	All	II,III,IV	−0.811	<.001	9	view →
LIHC	Male	All	+0.629	<.001	8	view →
UCEC	All	All	−1.920	<.001	6	view →
READ	All	All	−1.623	<.001	5	view →
CHOL	All	All	+1.056	<.001	4	view →
KICH	All	All	−0.614	<.001	4	view →
PAAD	All	All	+0.517	.011	4	view →
STAD	Female	All	−1.211	.008	3	view →
PRAD	All	All	−0.854	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

SLMAP–BLCA

Open the BLCA breakdown →