SLITRK3

Across TCGA patient cohorts, SLITRK3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,015 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLITRK3-associated genes across cancer lineages are MMP7, CDK16, and EHD4. Each is linked with SLITRK3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLITRK3-to-partner and partner-to-SLITRK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLITRK3 versus MMP7 in GBM, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLITRK3→partner) and Y-score (partner→SLITRK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MMP7 →	-1.433	-0.467	.001	.003	3	2
OV	CDK16 →	+1.033	+0.929	.001	<.001	3	1
OV	EHD4 →	+0.505	+1.006	<.001	<.001	3	1
OV	CEACAM5 →	+0.322	+1.048	<.001	<.001	3	1
OV	PPIF →	+1.326	+0.962	<.001	<.001	3	1
OV	ATP5F1B →	+0.507	+1.131	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,015 associations by consensus.

SLITRK3 vs MMP7 — GBM

Explore this scatter interactively →