SLCO1B3-SLCO1B7

Across TCGA patient cohorts, SLCO1B3-SLCO1B7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,431 significant associations in total. THCA shows the largest number of these associations.

The most reproducible SLCO1B3-SLCO1B7-associated GO terms across cancer lineages are Tetrapyrrole catabolic process, Pigment catabolic process, and Sodium-independent organic anion transport. Each is linked with SLCO1B3-SLCO1B7 in more than 9 cancer types. Because this analysis shows association rather than direction, both SLCO1B3-SLCO1B7-to-partner and partner-to-SLCO1B3-SLCO1B7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tetrapyrrole catabolic process grouped by SLCO1B3-SLCO1B7-low versus SLCO1B3-SLCO1B7-high in HNSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO1B3-SLCO1B7→partner) and Y-score (partner→SLCO1B3-SLCO1B7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Tetrapyrrole catabolic process →	-0.067	-0.060	<.001	<.001	3	10
HNSC	Pigment catabolic process →	-0.069	-0.059	<.001	<.001	3	10
STAD	Sodium-independent organic anion transport →	-0.064	-0.049	<.001	<.001	3	7
PRAD	Intracellular amino acid homeostasis →	+0.030	+0.070	<.001	<.001	3	6
ESCA	Positive regulation of pyroptosis →	+0.086	+0.095	<.001	.001	3	6
ESCA	Protein localization to site of double-strand break →	+0.040	+0.100	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,431 associations by consensus.

Tetrapyrrole catabolic process by SLCO1B3-SLCO1B7 expression — HNSC

Explore this box plot interactively →